QWO is the first and only FDA-approved injectable for moderate to severe cellulite. It is used in the buttocks and thighs to break down the fibrous bands that cause cellulite. Cellulite is not fat, it isn’t caused by what or how much you eat, or because you aren’t working out enough. Over time, skin thins, fat cells enlarge and push against the skin, and the fibrous bands under the skin thicken and cause tension and the signature dimpling on your buttocks and thighs. This is why many cellulite treatments that have come before QWO haven’t worked because they aren’t treating the root cause.